ok as of yesterday my graphic design copart and myself gave up on Vista. I finished migrating his core OS and apps back to XP Pro SP2. And I'm just about to format and do the same on my machine.
Most of his fonts and font management programs did not work at all. And a lot of my development tools, including Visual Studio 2005, did not work or work as expected in Vista. One of my major issues was the color management and the fact that nVidia has yet to release their monitor management feature. I was used to popping windows around my three screens by using a shortcut of CTRL-1 2 or 3 depending on the monitor. This one item is a major pain, now that it is gone.